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A hydroxamic acid is a class of organic compounds bearing the functional group RC(O)N(OH)R', with R and R' as organic residues and CO as a carbonyl group. They are amides (RC(O)NHR') wherein the NH center has an OH substitution. They are often used as metal chelators. ==Synthesis and reactions== Hydroxamic acids are prepared usually from esters or acid chlorides or carboxylic acids. For the synthesis of benzohydroxamic acid, the overall equations is:〔C. R. Hauser and W. B. Renfrow, Jr "Benzohydroxamic Acid" Org. Synth. 1939, volume 19, p. 15ff.〕 :C6H5CO2Me + NH2OH → C6H5C(O)NHOH + MeOH Hydroxamic acids can also be synthesized from aldehydes via the Angeli-Rimini reaction. A well-known hydroxamic acid reaction is the Lossen rearrangement. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「hydroxamic acid」の詳細全文を読む スポンサード リンク
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